Olive Leaf Extract is Effective Protection Against Ulcers
|January 23, 2013||Posted by admin under Research||
Olive leaf extract has been proven by modern research methods to live up to its reputation as an effective anti-microbial, antioxidant, immunoregulatory and anti-inflammatory supplement. The synergistic effect of its constituents in whole leaf extract has further been proven greater than the action of isolated constituents. Past medical traditions used the leaf for a variety of ailments, including those of the digestive system.
Assessing Gastroprotective Benefits of the Extract
Researchers sought to determine efficacy of the extract in protecting the stomach and small intestine from ulcers induced by means of ethanol. Five groups of rats were used, including a control. Experimental groups one through three received treatment with olive leaf dry extract at a rate of 40, 80, and 120 mg per kg, respectively. The fourth experimental group received 50 gm per kg of ranitidine, the generic name of a popular ulcer medication.
The extract was analyzed to confirm the constituents found in analyses from similar studies on olive leaf benefits. Researchers discovered that the extract used for this study did not some of the lesser constituents found in other analyses. This was likely due to natural variation in the species and different growing conditions.
Ethanol causes stomach ulcers by inhibiting gastroprotective enzymes and enhancing the effects of free radicals, and increasing lipid peroxidation. Rats fed ethanol showed an ulcer index value of 15 percent, which was reduced in group five to around 3 percent with the medication ranitidine. Experimental groups one through three all experienced comparable values between 2.5 and 5 percent with the 80 mg per kg dosage performing best.
Multiple Benefits and Safety
Histamine-2 blockers, such as ranitidine, work by suppressing production of gastric acid. Olive leaf extract at the proper dosage was shown to perform similarly, though the mechanism is protective and holistic. Olive leaf benefits are free from side effects common in pharmaceutical remedies.
For beneficial properties of olive leaf extract you might be interested in reading about all the benefits of this healthy natural supplement.